2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Cytochrome P450
  5. CYP2C9 Isoform
  6. CYP2C9 Inhibitor

CYP2C9 Inhibitor

CYP2C9 Inhibitors (2):

Cat. No. Product Name Effect Purity
  • HY-17643
    Oteseconazole
    		Inhibitor 99.46%
    Oteseconazole (VT-1161) is a potent and orally active anti-fungal agent. Oteseconazole potently binds to and inhibits Candida albicans cytochrome P45051 (CYP51) activity (Kd ≤39 nM), shows no obvious effect on human CYP51. Oteseconazole also can be used for the research of dermatophytes.
  • HY-164031
    Cloperidone
    		Inhibitor
    Cloperidone is an inhibitor for cytochrome P450 2C9 (CYP2C9) with an IC50 of 17.7 μM. Cloperidone exhibits cytotoxicity on HepG2 cells expressing CYP2C9 (60% survival rate at 10 μM).